A crucial role for RACK1 in the regulation of glucose-stimulated IRE1alpha activation in pancreatic beta cells.
第一作者:
Yifu,Qiu
第一单位:
Key Laboratory of Nutrition and Metabolism, Institute for Nutritional Sciences, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences, and Graduate School of the Chinese Academy of Sciences, Shanghai 200031, China.
作者:
医学主题词
动物(Animals);印迹法, 蛋白质(Blotting, Western);细胞系(Cell Line);细胞系, 肿瘤(Cell Line, Tumor);内质网(Endoplasmic Reticulum);内切核糖核酸酶类(Endoribonucleases);女(雌)性(Female);GTP结合蛋白质类(GTP-Binding Proteins);葡萄糖(Glucose);HT29细胞(HT29 Cells);人类(Humans);胰岛素(Insulin);胰岛素分泌细胞(Insulin-Secreting Cells);胰岛(Islets of Langerhans);男(雄)性(Male);小鼠(Mice);小鼠, 近交C57BL(Mice, Inbred C57BL);多蛋白复合物(Multiprotein Complexes);肿瘤蛋白质类(Neoplasm Proteins);肥胖症, 病态(Obesity, Morbid);磷酰化(Phosphorylation);蛋白质结合(Protein Binding);蛋白质磷酸酶2(Protein Phosphatase 2);受体, 细胞表面(Receptors, Cell Surface);逆转录聚合酶链反应(Reverse Transcriptase Polymerase Chain Reaction);双杂交系统技术(Two-Hybrid System Techniques)
DOI
10.1126/scisignal.2000514
PMID
20103773
发布时间
2025-05-29
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