Expression of the antimicrobial peptide alpha-defensin/cryptdins in intestinal crypts decreases at the initial phase of intestinal inflammation in a model of inflammatory bowel disease, IL-10-deficient mice.
作者:
主题词
动物(Animals);抗感染药(Anti-Infective Agents);印迹法, 蛋白质(Blotting, Western);疾病模型, 动物(Disease Models, Animal);炎症(Inflammation);炎性肠疾病(Inflammatory Bowel Diseases);白细胞介素10(Interleukin-10);肠黏膜(Intestinal Mucosa);肠(Intestines);小鼠(Mice);小鼠, 近交C57BL(Mice, Inbred C57BL);小鼠, 基因敲除(Mice, Knockout);蛋白质前体(Protein Precursors);RNA, 信使(RNA, Messenger);逆转录聚合酶链反应(Reverse Transcriptase Polymerase Chain Reaction);α防御素(alpha-Defensins)
DOI
10.1002/ibd.21253
PMID
20222124
发布时间
2018-12-01
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Inflammatory bowel diseases
1488-95页
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