Direct and coordinate regulation of ATP-binding cassette transporter genes by Myc factors generates specific transcription signatures that significantly affect the chemoresistance phenotype of cancer cells.
第一作者:
Antonio,Porro
第一单位:
Department of Biology, University of Bologna, Bologna 40126, Italy.
作者:
主题词
ATP结合匣式转运子(ATP-Binding Cassette Transporters);脑肿瘤(Brain Neoplasms);细胞系, 肿瘤(Cell Line, Tumor);抗药性, 肿瘤(Drug Resistance, Neoplasm);药物筛选试验, 抗肿瘤(Drug Screening Assays, Antitumor);基因表达谱(Gene Expression Profiling);人类(Humans);半数抑制浓度(Inhibitory Concentration 50);模型, 遗传学(Models, Genetic);肿瘤(Neoplasms);表型(Phenotype);原癌基因蛋白质c-myc(Proto-Oncogene Proteins c-myc);视网膜母细胞瘤(Retinoblastoma);转录因子(Transcription Factors);转录, 遗传(Transcription, Genetic)
DOI
10.1074/jbc.M109.078584
PMID
20233711
发布时间
2022-02-25
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