换一批Targeting the protein prenyltransferases efficiently reduces tumor development in mice with K-RAS-induced lung cancer.
第一作者：
Meng,Liu
第一单位：
Wallenberg Laboratory, Institute of Medicine, Sahlgrenska University Hospital, S-41345 Gothenburg, Sweden.
作者：
医学主题词
烷基和芳基转移酶类(Alkyl and Aryl Transferases);等位基因(Alleles);动物(Animals);细胞增殖(Cell Proliferation);细胞转化, 肿瘤(Cell Transformation, Neoplastic);二甲基丙基反转移酶(Dimethylallyltranstransferase);疾病模型, 动物(Disease Models, Animal);基因表达调控, 酶学(Gene Expression Regulation, Enzymologic);基因表达调控, 肿瘤(Gene Expression Regulation, Neoplastic);肺肿瘤(Lung Neoplasms);小鼠(Mice);小鼠, 基因敲除(Mice, Knockout);突变(Mutation);原癌基因蛋白质类p21(ras)(Proto-Oncogene Proteins p21(ras))
DOI
10.1073/pnas.0908396107
PMID
20308544
发布时间
2021-10-20
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