T-box 2 represses NDRG1 through an EGR1-dependent mechanism to drive the proliferation of breast cancer cells.
第一作者:
K L,Redmond
第一单位:
Centre for Cancer Research and Cell Biology, Queen's University Belfast, Belfast, UK.
作者:
主题词
印迹法, 蛋白质(Blotting, Western);乳腺肿瘤(Breast Neoplasms);细胞周期蛋白质类(Cell Cycle Proteins);细胞生长过程(Cell Growth Processes);细胞系, 肿瘤(Cell Line, Tumor);染色质免疫沉淀法(Chromatin Immunoprecipitation);早期生长反应蛋白质1(Early Growth Response Protein 1);女(雌)性(Female);基因表达调控, 肿瘤(Gene Expression Regulation, Neoplastic);人类(Humans);细胞内信号肽和蛋白质类(Intracellular Signaling Peptides and Proteins);启动区, 遗传(Promoter Regions, Genetic);RNA, 小分子干扰(RNA, Small Interfering);T盒域蛋白质类(T-Box Domain Proteins);转录, 遗传(Transcription, Genetic);转染(Transfection);增量调节(Up-Regulation)
DOI
10.1038/onc.2010.84
PMID
20348948
发布时间
2022-02-25
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Oncogene
3252-62页
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