The exon junction complex component Magoh controls brain size by regulating neural stem cell division.
作者:
主题词
1-烷基-2-乙酰甘油磷酸胆碱酯酶(1-Alkyl-2-acetylglycerophosphocholine Esterase);年龄因素(Age Factors);动物(Animals);动物, 新生(Animals, Newborn);细胞凋亡(Apoptosis);脑(Brain);溴脱氧尿苷(Bromodeoxyuridine);细胞分化(Cell Differentiation);细胞分裂(Cell Division);DNA突变分析(DNA Mutational Analysis);胚胎, 哺乳动物(Embryo, Mammalian);眼蛋白质类(Eye Proteins);基因表达谱(Gene Expression Profiling);基因表达调控, 发育期(Gene Expression Regulation, Developmental);基因型(Genotype);绿色荧光蛋白质类(Green Fluorescent Proteins);同源盒结构域蛋白质类(Homeodomain Proteins);人类(Humans);原位缺口末端标记(In Situ Nick-End Labeling);小鼠(Mice);小鼠, 近交C57BL(Mice, Inbred C57BL);小鼠, 转基因(Mice, Transgenic);小头畸形(Microcephaly);微管相关蛋白质类(Microtubule-Associated Proteins);突变(Mutation);神经组织蛋白质类(Nerve Tissue Proteins);神经发生(Neurogenesis);神经元(Neurons);核蛋白质类(Nuclear Proteins);寡核苷酸序列分析(Oligonucleotide Array Sequence Analysis);器官测量(Organ Size);成对盒转录因子类(Paired Box Transcription Factors);RNA干扰(RNA Interference);RNA, 信使(RNA, Messenger);阻遏蛋白质类(Repressor Proteins);干细胞(Stem Cells);T盒域蛋白质类(T-Box Domain Proteins);转染(Transfection)
DOI
10.1038/nn.2527
PMID
20364144
发布时间
2022-03-30
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Nature neuroscience
551-8页
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