Vaccination with synthetic analog peptides derived from WT1 oncoprotein induces T-cell responses in patients with complete remission from acute myeloid leukemia.
第一作者:
Peter G,Maslak
第一单位:
Leukemia Service, Department of Medicine, Sloan-Kettering Institute, Memorial Sloan-Kettering Cancer Center, 1275 York Avenue, New York, NY 10065, USA. maslakp@mskcc.org
作者:
医学主题词
成年人(Adult);老年人(Aged);CD4阳性T淋巴细胞(CD4-Positive T-Lymphocytes);CD8阳性T淋巴细胞(CD8-Positive T-Lymphocytes);癌症疫苗(Cancer Vaccines);细胞毒性, 免疫(Cytotoxicity, Immunologic);无病生存(Disease-Free Survival);女(雌)性(Female);HLA-A抗原(HLA-A Antigens);HLA-A2抗原(HLA-A2 Antigen);人类(Humans);超敏反应, 迟发型(Hypersensitivity, Delayed);干扰素γ(Interferon-gamma);Kaplan-Meiers评估(Kaplan-Meier Estimate);白血病, 髓样, 急性(Leukemia, Myeloid, Acute);男(雄)性(Male);中年人(Middle Aged);癌基因蛋白质类(Oncogene Proteins);试点项目(Pilot Projects);缓解诱导(Remission Induction);逆转录聚合酶链反应(Reverse Transcriptase Polymerase Chain Reaction);接种(Vaccination);疫苗, 亚单位(Vaccines, Subunit);WT1蛋白质类(WT1 Proteins);青年人(Young Adult)
DOI
10.1182/blood-2009-10-250993
PMID
20400682
发布时间
2022-04-09
基金项目
P01 CA023766/CA/NCI NIH HHS/United States
P30 CA008748/CA/NCI NIH HHS/United States
P01 23766/PHS HHS/United States
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