Inhibition of STAT3 and ErbB2 suppresses tumor growth, enhances radiosensitivity, and induces mitochondria-dependent apoptosis in glioma cells.
第一作者:
Ling,Gao
第一单位:
Department of Experimental Therapy of ARS, Beijing Institute of Radiation Medicine, Beijing, China.
作者:
医学主题词
动物(Animals);细胞凋亡(Apoptosis);星形细胞(Astrocytes);半胱氨酸天冬氨酸蛋白酶(Caspases);细胞系(Cell Line);细胞存活(Cell Survival);减量调节(Down-Regulation);酶激活(Enzyme Activation);神经胶质瘤(Glioma);小鼠(Mice);小鼠, 裸(Mice, Nude);线粒体(Mitochondria);肿瘤蛋白质类(Neoplasm Proteins);RNA, 小分子干扰(RNA, Small Interfering);辐射耐受性(Radiation Tolerance);大鼠(Rats);大鼠, Wistar(Rats, Wistar);STAT3转录因子(STAT3 Transcription Factor);转染(Transfection)
DOI
10.1016/j.ijrobp.2009.12.036
PMID
20610043
发布时间
2022-03-30
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