Synthesis of novel oxime-containing pyrazole derivatives and discovery of regulators for apoptosis and autophagy in A549 lung cancer cells.
第一作者:
Liang-Wen,Zheng
第一单位:
Institute of Organic Chemistry, School of Chemistry and Chemical Engineering, Shandong University, Jinan 250100, PR China.
作者:
医学主题词
抗肿瘤药(Antineoplastic Agents);细胞凋亡(Apoptosis);自噬(Autophagy);细胞系, 肿瘤(Cell Line, Tumor);结晶学, X线(Crystallography, X-Ray);药物评价, 临床前(Drug Evaluation, Preclinical);人类(Humans);肺肿瘤(Lung Neoplasms);分子构象(Molecular Conformation);肟类(Oximes);吡唑类(Pyrazoles);构效关系(Structure-Activity Relationship)
DOI
10.1016/j.bmcl.2010.06.121
PMID
20637610
发布时间
2012-11-15
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