换一批Sfpi1/PU.1 mutations in mouse radiation-induced acute myeloid leukaemias affect mRNA and protein abundance and associate with disrupted transcription.
第一作者：
N L,Brown
第一单位：
Health Protection Agency, Centre for Radiation, Chemical and Environmental Hazards, Chilton, Didcot, Oxon OX11 ORQ, UK.
作者：
医学主题词
动物(Animals);细胞系, 肿瘤(Cell Line, Tumor);细胞谱系(Cell Lineage);染色体, 人工, 细菌(Chromosomes, Artificial, Bacterial);基因表达调控, 肿瘤(Gene Expression Regulation, Neoplastic);免疫组织化学(Immunohistochemistry);原位杂交, 荧光(In Situ Hybridization, Fluorescence);白血病, 髓样, 急性(Leukemia, Myeloid, Acute);白血病, 辐射性(Leukemia, Radiation-Induced);小鼠(Mice);突变(Mutation);原癌基因蛋白质类(Proto-Oncogene Proteins);RNA, 信使(RNA, Messenger);逆转录聚合酶链反应(Reverse Transcriptase Polymerase Chain Reaction);反式激活因子类(Trans-Activators);转录, 遗传(Transcription, Genetic)
DOI
10.1016/j.leukres.2010.06.015
PMID
20638124
发布时间
2010-12-20
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Leukemia research
126-32页
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