Cross-species genomics matches driver mutations and cell compartments to model ependymoma.-论文-万方医学网

作者： Robert A,Johnson ^[1] ; Karen D,Wright ; Helen,Poppleton ; Kumarasamypet M,Mohankumar ; David,Finkelstein ; Stanley B,Pounds ; Vikki,Rand ; Sarah E S,Leary ; Elsie,White ; Christopher,Eden ; Twala,Hogg ; Paul,Northcott ; Stephen,Mack ; Geoffrey,Neale ; Yong-Dong,Wang ; Beth,Coyle ; Jennifer,Atkinson ; Mariko,DeWire ; Tanya A,Kranenburg ; Yancey,Gillespie ; Jeffrey C,Allen ; Thomas,Merchant ; Fredrick A,Boop ; Robert A,Sanford ; Amar,Gajjar ; David W,Ellison ; Michael D,Taylor ; Richard G,Grundy ; Richard J,Gilbertson

作者单位： Department of Developmental Neurobiology, St Jude Children's Research Hospital, 262 Danny Thomas Place, Memphis, Tennessee 38105, USA. ^[1]

主题词动物(Animals);细胞区室化(Cell Compartmentation);中枢神经系统(Central Nervous System);中枢神经系统肿瘤(Central Nervous System Neoplasms);疾病模型, 动物(Disease Models, Animal);室管膜瘤(Ependymoma);基因缺失(Gene Deletion);基因表达谱(Gene Expression Profiling);基因表达调控, 肿瘤(Gene Expression Regulation, Neoplastic);基因, p16(Genes, p16);基因组学(Genomics);人类(Humans);小鼠(Mice);模型, 生物学(Models, Biological);突变(Mutation);多态性, 单核苷酸(Polymorphism, Single Nucleotide);受体, EphB2(Receptor, EphB2);种特异性(Species Specificity);干细胞(Stem Cells);突触(Synapses)

DOI 10.1038/nature09173

PMID 20639864

发布时间 2022-03-17

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Cross-species genomics matches driver mutations and cell compartments to model ependymoma.

Nature

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Cross-species genomics matches driver mutations and cell compartments to model ependymoma.

Nature

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