换一批
换一批A novel water-soluble gossypol derivative increases chemotherapeutic sensitivity and promotes growth inhibition in colon cancer.
第一作者：
Fei,Yan
第一单位：
Laboratory of Targeted Cancer Therapy, Institute of Health Sciences, Shanghai Institutes for Biological Sciences of Chinese Academy of Sciences & Shanghai Jiao-Tong University School of Medicine (SJTU-SM), Shanghai 200025, China.
作者：
主题词
动物(Animals);抗肿瘤药(Antineoplastic Agents);细胞凋亡(Apoptosis);细胞系, 肿瘤(Cell Line, Tumor);细胞增殖(Cell Proliferation);细胞存活(Cell Survival);结肠肿瘤(Colonic Neoplasms);药物筛选试验, 抗肿瘤(Drug Screening Assays, Antitumor);药物协同作用(Drug Synergism);氟尿嘧啶(Fluorouracil);棉酚(Gossypol);人类(Humans);小鼠(Mice);小鼠, 近交BALB C(Mice, Inbred BALB C);模型, 分子(Models, Molecular);肿瘤移植(Neoplasm Transplantation);青霉胺(Penicillamine);蛋白质结合(Protein Binding);原癌基因蛋白质c-bcl-2(Proto-Oncogene Proteins c-bcl-2);溶解度(Solubility);立体异构现象(Stereoisomerism);构效关系(Structure-Activity Relationship);水(Water)
DOI
10.1021/jm1001698
PMID
20684596
发布时间
2013-11-21
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