Elevated systemic elimination of cimetidine in rats with acute biliary obstruction: the role of renal organic cation transporter OCT2.
第一作者:
Tomohiko,Kurata
第一单位:
Department of Clinical Pharmacy and Biopharmaceutics, Mie University Graduate School of Medicine, Tsu, Mie, Japan.
作者:
主题词
急性病(Acute Disease);动物(Animals);反向转运物(Antiporters);儿茶酚胺质膜转运蛋白质类(Catecholamine Plasma Membrane Transport Proteins);胆汁淤积(Cholestasis);西咪替丁(Cimetidine);组胺H2拮抗剂(Histamine H2 Antagonists);肾(Kidney);男(雄)性(Male);代谢清除率(Metabolic Clearance Rate);有机阳离子转运蛋白质类(Organic Cation Transport Proteins);大鼠(Rats);大鼠, Wistar(Rats, Wistar);睾酮(Testosterone)
DOI
10.2133/dmpk.dmpk-10-rg-004
PMID
20814153
发布时间
2020-03-11
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