Loss of miR-200 inhibition of Suz12 leads to polycomb-mediated repression required for the formation and maintenance of cancer stem cells.
第一作者:
Dimitrios,Iliopoulos
第一单位:
Department Biological Chemistry and Molecular Pharmacology, Harvard Medical School, Boston, MA 02115, USA.
作者:
主题词
动物(Animals);乳腺肿瘤(Breast Neoplasms);钙黏着糖蛋白类(Cadherins);载体蛋白质类(Carrier Proteins);细胞系, 肿瘤(Cell Line, Tumor);女(雌)性(Female);人类(Humans);小鼠(Mice);小鼠, 裸(Mice, Nude);微RNAs(MicroRNAs);肿瘤蛋白质类(Neoplasm Proteins);肿瘤移植(Neoplasm Transplantation);肿瘤干细胞(Neoplastic Stem Cells);核蛋白质类(Nuclear Proteins);RNA, 肿瘤(RNA, Neoplasm);阻遏蛋白质类(Repressor Proteins);转录因子(Transcription Factors);移植, 异种(Transplantation, Heterologous)
DOI
10.1016/j.molcel.2010.08.013
PMID
20832727
发布时间
2021-12-03
- 浏览3

Molecular cell
761-72页
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