Endoglin differentially regulates TGF-β-induced Smad2/3 and Smad1/5 signalling and its expression correlates with extracellular matrix production and cellular differentiation state in human chondrocytes.
第一作者:
K W,Finnson
第一单位:
Division of Plastic Surgery, Department of Surgery, McGill University, Montreal, Quebec, Canada.
作者:
医学主题词
抗原, CD(Antigens, CD);印迹法, 蛋白质(Blotting, Western);软骨, 关节(Cartilage, Articular);细胞分化(Cell Differentiation);细胞, 培养的(Cells, Cultured);软骨细胞(Chondrocytes);细胞外基质(Extracellular Matrix);基因表达调控(Gene Expression Regulation);人类(Humans);免疫组织化学(Immunohistochemistry);骨关节炎(Osteoarthritis);磷酰化(Phosphorylation);受体, 细胞表面(Receptors, Cell Surface);Smad蛋白质类, 受体调节性(Smad Proteins, Receptor-Regulated);转化生长因子β(Transforming Growth Factor beta)
DOI
10.1016/j.joca.2010.09.002
PMID
20833252
发布时间
2025-05-29
基金项目
- 浏览4
Osteoarthritis and cartilage
1518-27页
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