The Wnt/planar cell polarity protein-tyrosine kinase-7 (PTK7) is a highly efficient proteolytic target of membrane type-1 matrix metalloproteinase: implications in cancer and embryogenesis.
作者:
主题词
动物(Animals);结合部位(Binding Sites);细胞黏附分子(Cell Adhesion Molecules);细胞系(Cell Line);细胞系, 肿瘤(Cell Line, Tumor);细胞运动(Cell Movement);细胞极性(Cell Polarity);细胞骨架(Cytoskeleton);胚胎, 非哺乳动物(Embryo, Nonmammalian);基因表达调控, 发育期(Gene Expression Regulation, Developmental);基因敲低技术(Gene Knockdown Techniques);人类(Humans);原位杂交(In Situ Hybridization);基质金属蛋白酶14(Matrix Metalloproteinase 14);分子序列数据(Molecular Sequence Data);突变(Mutation);肿瘤(Neoplasms);蛋白质结合(Protein Binding);蛋白质结构, 三级(Protein Structure, Tertiary);受体蛋白质酪氨酸激酶类(Receptor Protein-Tyrosine Kinases);逆转录聚合酶链反应(Reverse Transcriptase Polymerase Chain Reaction);信号传导(Signal Transduction);转染(Transfection);Wnt蛋白质类(Wnt Proteins);斑马鱼(Zebrafish);斑马鱼蛋白质类(Zebrafish Proteins)
DOI
10.1074/jbc.M110.165159
PMID
20837484
发布时间
2022-02-23
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