T cells expressing constitutively active Akt resist multiple tumor-associated inhibitory mechanisms.
作者:
主题词
细胞凋亡(Apoptosis);印迹法, 蛋白质(Blotting, Western);细胞增殖(Cell Proliferation);流式细胞术(Flow Cytometry);神经节苷脂类(Gangliosides);人类(Humans);淋巴细胞活化(Lymphocyte Activation);NF-κB(NF-kappa B);神经母细胞瘤(Neuroblastoma);原癌基因蛋白质c-akt(Proto-Oncogene Proteins c-akt);RNA, 信使(RNA, Messenger);逆转录聚合酶链反应(Reverse Transcriptase Polymerase Chain Reaction);信号传导(Signal Transduction);T淋巴细胞(T-Lymphocytes);T淋巴细胞, 调节性(T-Lymphocytes, Regulatory);转导, 遗传(Transduction, Genetic);转化生长因子β(Transforming Growth Factor beta);肿瘤负荷(Tumor Burden);肿瘤细胞, 培养的(Tumor Cells, Cultured)
DOI
10.1038/mt.2010.185
PMID
20842106
发布时间
2022-04-01
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Molecular therapy
2006-17页
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