Development and validation of a high-performance liquid chromatography-tandem mass spectrometry method for the determination of the novel proteasome inhibitor CEP-18770 in human plasma and its application in a clinical pharmacokinetic study.
作者:
主题词
乙腈类(Acetonitriles);联苯化合物(Biphenyl Compounds);硼酸化物(Boronic Acids);色谱法, 高压液相(Chromatography, High Pressure Liquid);临床试验, Ⅰ期(主题)(Clinical Trials, Phase I as Topic);药物稳定性(Drug Stability);人类(Humans);多发性骨髓瘤(Multiple Myeloma);肿瘤(Neoplasms);结果可重复性(Reproducibility of Results);敏感性与特异性(Sensitivity and Specificity);串联质谱法(Tandem Mass Spectrometry);四唑类(Tetrazoles);苏氨酸(Threonine)
DOI
10.1002/jms.1842
PMID
20872901
发布时间
2018-12-01
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Journal of mass spectrometry
1299-305页
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