Population pharmacokinetic modeling of the association between 63396C->T pregnane X receptor polymorphism and unboosted atazanavir clearance.
第一作者:
Alessandro,Schipani
第一单位:
Department of Pharmacology and Therapeutics, University of Liverpool, 70 Pembroke Place, Liverpool L69 3GF, United Kingdom.
作者:
医学主题词
成年人(Adult);老年人(Aged);昼夜节律(Circadian Rhythm);细胞色素P-450 CYP3A(Cytochrome P-450 CYP3A);女(雌)性(Female);基因频率(Gene Frequency);基因型(Genotype);HIV感染(HIV Infections);人类(Humans);男(雄)性(Male);中年人(Middle Aged);寡肽类(Oligopeptides);有机阴离子转运子(Organic Anion Transporters);多态性, 单核苷酸(Polymorphism, Single Nucleotide);吡啶类(Pyridines);受体, 类固醇(Receptors, Steroid);青年人(Young Adult)
DOI
10.1128/AAC.00781-10
PMID
20921307
发布时间
2022-03-16
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