Protein kinase WNK1 promotes cell surface expression of glucose transporter GLUT1 by regulating a Tre-2/USP6-BUB2-Cdc16 domain family member 4 (TBC1D4)-Rab8A complex.
作者:
主题词
14-3-3蛋白质类(14-3-3 Proteins);生物转运(Biological Transport);胞吐作用(Exocytosis);GTP酶激活蛋白质类(GTPase-Activating Proteins);基因表达调控(Gene Expression Regulation);基因沉默(Gene Silencing);葡萄糖(Glucose);葡萄糖转运体1型(Glucose Transporter Type 1);葡萄糖转运体4型(Glucose Transporter Type 4);HEK293细胞(HEK293 Cells);人类(Humans);细胞内信号肽和蛋白质类(Intracellular Signaling Peptides and Proteins);次要组织相容性抗原(Minor Histocompatibility Antigens);寡核苷酸类(Oligonucleotides);RNA, 小分子干扰(RNA, Small Interfering);rab GTP结合蛋白质类(rab GTP-Binding Proteins)
DOI
10.1074/jbc.M110.159418
PMID
20937822
发布时间
2021-12-03
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