Association of the variants CASP8 D302H and CASP10 V410I with breast and ovarian cancer risk in BRCA1 and BRCA2 mutation carriers.
第一作者:
Christoph,Engel
第一单位:
Institute for Medical Informatics, Statistics and Epidemiology, University of Leipzig, Leipzig, Germany.
作者:
医学主题词
乳腺肿瘤(Breast Neoplasms);半胱氨酸天冬氨酸蛋白酶10(Caspase 10);半胱氨酸天冬氨酸蛋白酶8(Caspase 8);女(雌)性(Female);基因, BRCA1(Genes, BRCA1);基因, BRCA2(Genes, BRCA2);疾病遗传易感性(Genetic Predisposition to Disease);基因型(Genotype);人类(Humans);突变(Mutation);卵巢肿瘤(Ovarian Neoplasms);聚合酶链反应(Polymerase Chain Reaction);多态性, 单核苷酸(Polymorphism, Single Nucleotide);危险因素(Risk Factors)
DOI
10.1158/1055-9965.EPI-10-0517
PMID
20978178
发布时间
2025-05-29
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