Identification of epidermal Pdx1 expression discloses different roles of Notch1 and Notch2 in murine Kras(G12D)-induced skin carcinogenesis in vivo.
作者:
主题词
动物(Animals);碱基序列(Base Sequence);癌, 鳞状细胞(Carcinoma, Squamous Cell);细胞, 培养的(Cells, Cultured);DNA引物(DNA Primers);表皮(Epidermis);基因, ras(Genes, ras);同源盒结构域蛋白质类(Homeodomain Proteins);小鼠(Mice);小鼠, 基因敲除(Mice, Knockout);乳头状瘤(Papilloma);受体, Notch1(Receptor, Notch1);受体, Notch2(Receptor, Notch2);逆转录聚合酶链反应(Reverse Transcriptase Polymerase Chain Reaction);皮肤(Skin);皮肤肿瘤(Skin Neoplasms);反式激活因子类(Trans-Activators);β连环素(beta Catenin)
DOI
10.1371/journal.pone.0013578
PMID
21042537
发布时间
2021-10-20
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PloS one
e13578页
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