换一批Comparison of intrinsic clearances in human liver microsomes and suspended hepatocytes from the same donor livers: clearance-dependent relationship and implications for prediction of in vivo clearance.
第一作者：
Joanne A,Foster
第一单位：
Centre for Applied Pharmacokinetic Research, School of Pharmacy and Pharmaceutical Sciences, University of Manchester, Manchester, UK.
作者：
主题词
细胞色素P450酶系统(Cytochrome P-450 Enzyme System);酶测定(Enzyme Assays);肝细胞(Hepatocytes);人类(Humans);动力学(Kinetics);质谱分析法(Mass Spectrometry);代谢清除率(Metabolic Clearance Rate);代谢网络和途径(Metabolic Networks and Pathways);微粒体, 肝(Microsomes, Liver);底物特异性(Substrate Specificity);组织供者(Tissue Donors)
DOI
10.3109/00498254.2010.530700
PMID
21058916
发布时间
2011-01-11
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