Tamm-Horsfall glycoprotein interacts with renal outer medullary potassium channel ROMK2 and regulates its function.
第一作者:
Aparna,Renigunta
第一单位:
Department of Pediatric Nephrology, Children's Hospital, Philipps University of Marburg, Baldingerstr., 35043 Marburg, Germany. renigunt@med.uni-marburg.de
作者:
医学主题词
动物(Animals);痛风(Gout);人类(Humans);高尿酸血症(Hyperuricemia);离子转运(Ion Transport);肾(Kidney);肾疾病(Kidney Diseases);肾疾病, 囊性(Kidney Diseases, Cystic);膜电位(Membrane Potentials);小鼠(Mice);小鼠, 基因敲除(Mice, Knockout);突变(Mutation);卵母细胞(Oocytes);多囊肾, 常染色体显性(Polycystic Kidney, Autosomal Dominant);钾通道, 内向整流(Potassium Channels, Inwardly Rectifying);酿酒酵母菌(Saccharomyces cerevisiae);双杂交系统技术(Two-Hybrid System Techniques);尿调节素(Uromodulin);光滑爪蟾(Xenopus laevis)
DOI
10.1074/jbc.M110.149880
PMID
21081491
发布时间
2021-10-20
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