The effect of down-regulation of Smad3 by RNAi on hepatic stellate cells and a carbon tetrachloride-induced rat model of hepatic fibrosis.
第一作者:
Z R,Wang
第一单位:
Department of Biochemistry and Molecular Biology, Soochow University, Suzhou, China.
作者:
主题词
动物(Animals);四氯化碳(Carbon Tetrachloride);胶原(Collagen);减量调节(Down-Regulation);肝星状细胞(Hepatic Stellate Cells);脂质体(Liposomes);肝硬化, 实验性(Liver Cirrhosis, Experimental);男(雄)性(Male);质粒(Plasmids);RNA干扰(RNA Interference);RNA, 信使(RNA, Messenger);RNA, 小分子干扰(RNA, Small Interfering);放射免疫测定(Radioimmunoassay);随机分配(Random Allocation);大鼠(Rats);大鼠, Sprague-Dawley(Rats, Sprague-Dawley);逆转录聚合酶链反应(Reverse Transcriptase Polymerase Chain Reaction);疾病严重程度指数(Severity of Illness Index);Smad3蛋白质(Smad3 Protein);转染(Transfection);转化生长因子β1(Transforming Growth Factor beta1)
DOI
10.1590/s0100-879x2010007500132
PMID
21103786
发布时间
2019-06-06
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