换一批Aromatase is a direct target of FOXL2: C134W in granulosa cell tumors via a single highly conserved binding site in the ovarian specific promoter.
第一作者：
Nicholas I,Fleming
第一单位：
Prince Henry's Institute of Medical Research, Clayton, Victoria, Australia.
作者：
医学主题词
芳香酶(Aromatase);结合部位(Binding Sites);细胞系, 肿瘤(Cell Line, Tumor);女(雌)性(Female);叉头转录因子类(Forkhead Transcription Factors);基因表达调控, 肿瘤(Gene Expression Regulation, Neoplastic);粒层细胞瘤(Granulosa Cell Tumor);人类(Humans);诱变, 定点(Mutagenesis, Site-Directed);突变(Mutation);卵巢肿瘤(Ovarian Neoplasms);磷蛋白类(Phosphoproteins);点突变(Point Mutation);启动区, 遗传(Promoter Regions, Genetic);调控序列, 核酸(Regulatory Sequences, Nucleic Acid)
DOI
10.1371/journal.pone.0014389
PMID
21188138
发布时间
2025-01-03
- 浏览37
PloS one
e14389页
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