Highly specific auto-antibodies against claudin-18 isoform 2 induced by a chimeric HBcAg virus-like particle vaccine kill tumor cells and inhibit the growth of lung metastases.
第一作者:
Thorsten,Klamp
第一单位:
Department of Internal Medicine III, Translational and Experimental Oncology, and Institute of Zoology, Johannes Gutenberg-University, Innsbruck, Austria.
作者:
主题词
腺癌(Adenocarcinoma);氨基酸序列(Amino Acid Sequence);动物(Animals);抗体特异性(Antibody Specificity);抗体依赖细胞细胞毒性(Antibody-Dependent Cell Cytotoxicity);自身抗体(Autoantibodies);CHO细胞(CHO Cells);癌症疫苗(Cancer Vaccines);细胞系, 肿瘤(Cell Line, Tumor);壳牢素类(Claudins);仓鼠亚科(Cricetinae);仓鼠属(Cricetulus);HEK293细胞(HEK293 Cells);乙型肝炎核心抗原(Hepatitis B Core Antigens);乙型肝炎病毒(Hepatitis B virus);人类(Humans);肺肿瘤(Lung Neoplasms);膜蛋白质类(Membrane Proteins);小鼠(Mice);小鼠, 近交BALB C(Mice, Inbred BALB C);分子序列数据(Molecular Sequence Data);蛋白质亚型(Protein Isoforms);兔(Rabbits);胃肿瘤(Stomach Neoplasms);疫苗, 病毒样颗粒(Vaccines, Virus-Like Particle)
DOI
10.1158/0008-5472.CAN-10-2292
PMID
21224362
发布时间
2012-11-15
- 浏览25
Cancer research
516-27页
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