Overexpression of Enhancer of zeste homolog 2 with trimethylation of lysine 27 on histone H3 in adult T-cell leukemia/lymphoma as a target for epigenetic therapy.
作者:
主题词
腺苷(Adenosine);碱基序列(Base Sequence);印迹法, 蛋白质(Blotting, Western);CD4阳性T淋巴细胞(CD4-Positive T-Lymphocytes);细胞系, 肿瘤(Cell Line, Tumor);细胞增殖(Cell Proliferation);DNA结合蛋白质类(DNA-Binding Proteins);表观基因组学(Epigenomics);基因表达谱(Gene Expression Profiling);基因表达调控, 白血病(Gene Expression Regulation, Leukemic);组蛋白类(Histones);人类(Humans);羟肟酸类(Hydroxamic Acids);吲哚类(Indoles);细胞内信号肽和蛋白质类(Intracellular Signaling Peptides and Proteins);白血病淋巴瘤, 成人T细胞(Leukemia-Lymphoma, Adult T-Cell);赖氨酸(Lysine);甲基化(Methylation);微RNAs(MicroRNAs);寡核苷酸序列分析(Oligonucleotide Array Sequence Analysis);阻遏蛋白质类(Repressor Proteins);逆转录聚合酶链反应(Reverse Transcriptase Polymerase Chain Reaction);转录因子(Transcription Factors)
DOI
10.3324/haematol.2010.028605
PMID
21228036
发布时间
2021-10-20
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Haematologica
712-9页
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