换一批CTGF/CCN2 activates canonical Wnt signalling in mesangial cells through LRP6: implications for the pathogenesis of diabetic nephropathy.
第一作者：
Brian,Rooney
第一单位：
UCD Diabetes Research Centre, UCD School of Biomolecular and Biomedical Science, University College Dublin, Belfield, Dublin 4, Ireland.
作者：
医学主题词
动物(Animals);细胞, 培养的(Cells, Cultured);结缔组织生长因子(Connective Tissue Growth Factor);糖尿病, 1型(Diabetes Mellitus, Type 1);糖尿病肾病(Diabetic Nephropathies);糖原合成酶激酶3(Glycogen Synthase Kinase 3);人类(Humans);高血糖症(Hyperglycemia);高血压(Hypertension);肾皮质(Kidney Cortex);LDL受体相关蛋白质类(LDL-Receptor Related Proteins);男(雄)性(Male);肾小球系膜细胞(Mesangial Cells);小鼠(Mice);小鼠, 近交C57BL(Mice, Inbred C57BL);磷酰化(Phosphorylation);蛋白质转运(Protein Transport);RNA, 小分子干扰(RNA, Small Interfering);信号传导(Signal Transduction);输尿管梗阻(Ureteral Obstruction);Wnt蛋白质类(Wnt Proteins);β连环素(beta Catenin)
DOI
10.1016/j.febslet.2011.01.004
PMID
21237163
发布时间
2019-12-10
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FEBS letters
531-8页
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