Modular bioreactor for primary human hepatocyte culture: medium flow stimulates expression and activity of detoxification genes.
第一作者:
Bruna,Vinci
第一单位:
Centro Interdipartimentale di Ricerca E. Piaggio, Faculty of Engineering, University of Pisa, Pisa, Italy.
作者:
主题词
芳基烃羟化酶类(Aryl Hydrocarbon Hydroxylases);生物反应器(Bioreactors);细胞, 培养的(Cells, Cultured);细胞色素P450 CYP1A1(Cytochrome P-450 CYP1A1);细胞色素P450 CYP1A2(Cytochrome P-450 CYP1A2);葡糖醛酸基转移酶(Glucuronosyltransferase);谷胱甘肽转移酶(Glutathione Transferase);肝细胞(Hepatocytes);人类(Humans);氧化还原酶类, N-脱甲基(Oxidoreductases, N-Demethylating);逆转录聚合酶链反应(Reverse Transcriptase Polymerase Chain Reaction);抗剪切强度(Shear Strength)
DOI
10.1002/biot.201000326
PMID
21259441
发布时间
2023-12-13
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Biotechnology journal
554-64页
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