Thermodynamic, enzymatic and structural effects of removing a salt bridge at the base of loop 4 in (pro)caspase-3.
第一作者:
Jad,Walters
第一单位:
Department of Molecular and Structural Biochemistry, North Carolina State University, Raleigh, NC 27695-7622, USA.
作者:
医学主题词
半胱氨酸天冬氨酸蛋白酶3(Caspase 3);催化域(Catalytic Domain);结晶学, X线(Crystallography, X-Ray);酶稳定性(Enzyme Stability);氢键合(Hydrogen Bonding);模型, 分子(Models, Molecular);突变(Mutation);蛋白质折叠(Protein Folding);静电(Static Electricity);构效关系(Structure-Activity Relationship);热力学(Thermodynamics)
DOI
10.1016/j.abb.2011.01.011
PMID
21266160
发布时间
2025-05-29
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