Comparing the effect of hydroxyethyl starch 130/0.4 with balanced crystalloid solution on mortality and kidney failure in patients with severe sepsis (6S--Scandinavian Starch for Severe Sepsis/Septic Shock trial): study protocol, design and rationale for a double-blinded, randomised clinical trial.

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第一作者： Anders,Perner

第一单位： Department of Intensive Care, Centre of Clinical Intervention Research, Copenhagen University Hospital, Rigshospitalet, Denmark. anders.perner@rh.regionh.dk

作者： Anders,Perner ^[1] ; Nicolai,Haase ; Jørn,Wetterslev ; Anders,Aneman ; Jyrki,Tenhunen ; Anne Berit,Guttormsen ; Gudmundur,Klemenzson ; Frank,Pott ; Karen Doris,Bødker ; Per Martin,Bådstøløkken ; Asger,Bendtsen ; Peter,Søe-Jensen ; Hamid,Tousi ; Morten,Bestle ; Malgorzata,Pawlowicz ; Robert,Winding ; Hans-Henrik,Bülow ; Claude,Kancir ; Morten,Steensen ; Jonas,Nielsen ; Bjarne,Fogh ; Kristian R,Madsen ; Nils H,Larsen ; Marcela,Carlsson ; Jørgen,Wiis ; John Asger,Petersen ; Susanne,Iversen ; Ole,Schøidt ; Siv,Leivdal ; Pawel,Berezowicz ; Ville,Pettilä ; Esko,Ruokonen ; Pål,Klepstad ; Sari,Karlsson ; Maija,Kaukonen ; Juha,Rutanen ; Sigurbergur,Karason ; Anne Lene,Kjældgaard ; Lars Broksø,Holst ; Jan,Wernerman ; Scandinavian Critical Care Trials Group

作者单位： Department of Intensive Care, Centre of Clinical Intervention Research, Copenhagen University Hospital, Rigshospitalet, Denmark. anders.perner@rh.regionh.dk ^[1]

主题词成年人(Adult);双盲法(Double-Blind Method);人类(Humans);等渗溶液(Isotonic Solutions);分子量(Molecular Weight);血浆代用品(Plasma Substitutes);肾功能不全(Renal Insufficiency);研究设计(Research Design);脓毒症(Sepsis);疾病严重程度指数(Severity of Illness Index)

DOI 10.1186/1745-6215-12-24

PMID 21269526

发布时间 2022-03-09

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Comparing the effect of hydroxyethyl starch 130/0.4 with balanced crystalloid solution on mortality and kidney failure in patients with severe sepsis (6S--Scandinavian Starch for Severe Sepsis/Septic Shock trial): study protocol, design and rationale for a double-blinded, randomised clinical trial.

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Comparing the effect of hydroxyethyl starch 130/0.4 with balanced crystalloid solution on mortality and kidney failure in patients with severe sepsis (6S--Scandinavian Starch for Severe Sepsis/Septic Shock trial): study protocol, design and rationale for a double-blinded, randomised clinical trial.

Trials

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