Pdx1- and Ngn3-Cre-mediated PLAG1 expression in the pancreas leads to endocrine hormone imbalances that affect glucose metabolism.
第一作者:
Jeroen,Declercq
第一单位:
Stem Cell Institute, Katholieke Universiteit Leuven, Leuven, Belgium. Jeroen.declercq@med.kuleuven.be
作者:
主题词
动物(Animals);碱性螺旋-环-螺旋转录因子类(Basic Helix-Loop-Helix Transcription Factors);细胞增殖(Cell Proliferation);DNA结合蛋白质类(DNA-Binding Proteins);胰高血糖素(Glucagon);葡萄糖(Glucose);葡糖耐量试验(Glucose Tolerance Test);同源盒结构域蛋白质类(Homeodomain Proteins);内环境稳定(Homeostasis);增生(Hyperplasia);低血糖症(Hypoglycemia);胰岛素(Insulin);整合酶类(Integrases);胰岛(Islets of Langerhans);胰岛移植(Islets of Langerhans Transplantation);小鼠(Mice);小鼠, 转基因(Mice, Transgenic);神经组织蛋白质类(Nerve Tissue Proteins);器官测量(Organ Size);胰腺激素类(Pancreatic Hormones);生长抑素(Somatostatin);时间因素(Time Factors);反式激活因子类(Trans-Activators)
DOI
10.3727/096368910X550242
PMID
21294959
发布时间
2013-11-21
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Cell transplantation
1285-97页
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