The expression of the ubiquitin ligase SIAH2 (seven in absentia homolog 2) is mediated through gene copy number in breast cancer and is associated with a basal-like phenotype and p53 expression.
第一作者:
Peter,Chan
第一单位:
Department of Pathology, Peter MacCallum Cancer Centre, Locked Bag 1 A'Beckett Street, Melbourne, Victoria 8006, Australia.
作者:
医学主题词
成年人(Adult);老年人(Aged);老年人, 80以上(Aged, 80 and over);乳腺肿瘤(Breast Neoplasms);队列研究(Cohort Studies);DNA甲基化(DNA Methylation);女(雌)性(Female);基因剂量(Gene Dosage);基因表达(Gene Expression);人类(Humans);Kaplan-Meiers评估(Kaplan-Meier Estimate);乳腺, 人(Mammary Glands, Human);中年人(Middle Aged);肿瘤分期(Neoplasm Staging);核蛋白质类(Nuclear Proteins);表型(Phenotype);启动区, 遗传(Promoter Regions, Genetic);肿瘤抑制蛋白质p53(Tumor Suppressor Protein p53);泛素蛋白连接酶类(Ubiquitin-Protein Ligases);青年人(Young Adult)
DOI
10.1186/bcr2828
PMID
21306611
发布时间
2025-05-29
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