Anti-tumor effect in human breast cancer by TAE226, a dual inhibitor for FAK and IGF-IR in vitro and in vivo.
第一作者:
Naito,Kurio
第一单位:
Department of Oral and Maxillofacial Surgery, Okayama University Graduate School of Medicine, Okayama, Japan.
作者:
主题词
动物(Animals);骨肿瘤(Bone Neoplasms);乳腺肿瘤(Breast Neoplasms);细胞系(Cell Line);细胞, 培养的(Cells, Cultured);女(雌)性(Female);黏着斑蛋白酪氨酸激酶类(Focal Adhesion Protein-Tyrosine Kinases);人类(Humans);巨噬细胞(Macrophages);小鼠(Mice);小鼠, 近交BALB C(Mice, Inbred BALB C);小鼠, 近交C57BL(Mice, Inbred C57BL);小鼠, 裸(Mice, Nude);吗啉类(Morpholines);肿瘤转移(Neoplasm Metastasis);肿瘤移植(Neoplasm Transplantation);破骨细胞(Osteoclasts);甲状旁腺激素相关蛋白质(Parathyroid Hormone-Related Protein);RANK配体(RANK Ligand);受体, IGF1型(Receptor, IGF Type 1);间质细胞(Stromal Cells)
DOI
10.1016/j.yexcr.2011.02.008
PMID
21338601
发布时间
2011-04-04
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Experimental cell research
1134-46页
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