Role of G(i/o)-Src kinase-PI3K/Akt pathway and caveolin-1 in β₂-adrenoceptor coupling to endothelial NO synthase in mouse pulmonary artery.
作者:
主题词
乙酰胆碱(Acetylcholine);肾上腺素能β-2受体激动剂(Adrenergic beta-2 Receptor Agonists);动物(Animals);细胞质膜微囊(Caveolae);窖蛋白1(Caveolin 1);地诺前列素(Dinoprost);内皮, 血管(Endothelium, Vascular);酶抑制剂(Enzyme Inhibitors);GTP结合蛋白质α亚单位, Gi-Go(GTP-Binding Protein alpha Subunits, Gi-Go);基因缺失(Gene Deletion);男(雄)性(Male);小鼠(Mice);小鼠, 近交C57BL(Mice, Inbred C57BL);小鼠, 基因敲除(Mice, Knockout);一氧化氮合酶Ⅲ型(Nitric Oxide Synthase Type III);百白咳毒素(Pertussis Toxin);磷酰化(Phosphorylation);磷酸转移酶类(醇族体)(Phosphotransferases (Alcohol Group Acceptor));丙卡特罗(Procaterol);蛋白质加工, 转译后(Protein Processing, Post-Translational);肺动脉(Pulmonary Artery);受体, 肾上腺素能β2(Receptors, Adrenergic, beta-2);信号传导(Signal Transduction);血管舒张药(Vasodilator Agents)
DOI
10.1016/j.cellsig.2011.02.008
PMID
21385608
发布时间
2014-11-20
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Cellular signalling
1136-43页
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