换一批Efficacy of ganitumab (AMG 479), alone and in combination with rapamycin, in Ewing's and osteogenic sarcoma models.
第一作者：
Pedro J,Beltran
第一单位：
Oncology Research Therapeutic Area, Amgen Inc., One Amgen Center Drive, Thousand Oaks, CA 91320, USA. pbeltran@amgen.com
作者：
医学主题词
动物(Animals);抗生素类, 抗肿瘤(Antibiotics, Antineoplastic);抗体, 单克隆(Antibodies, Monoclonal);抗肿瘤联合化疗方案(Antineoplastic Combined Chemotherapy Protocols);骨肿瘤(Bone Neoplasms);半胱氨酸天冬氨酸蛋白酶3(Caspase 3);细胞系, 肿瘤(Cell Line, Tumor);细胞增殖(Cell Proliferation);女(雌)性(Female);人类(Humans);胰岛素样生长因子Ⅰ(Insulin-Like Growth Factor I);小鼠(Mice);小鼠, 裸(Mice, Nude);骨肉瘤(Osteosarcoma);磷酰化(Phosphorylation);受体, IGF1型(Receptor, IGF Type 1);受体, 胰岛素(Receptor, Insulin);信号传导(Signal Transduction);西罗莫司(Sirolimus);异种移植模型抗肿瘤试验(Xenograft Model Antitumor Assays)
DOI
10.1124/jpet.110.178400
PMID
21385891
发布时间
2025-03-06
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