Successful treatment of metastatic melanoma by adoptive transfer of blood-derived polyclonal tumor-specific CD4+ and CD8+ T cells in combination with low-dose interferon-alpha.
第一作者:
Els M E,Verdegaal
第一单位:
Department of Clinical Oncology, Leiden University Medical Center, Leiden, The Netherlands. e.verdegaal@lumc.nl
作者:
主题词
过继转移(Adoptive Transfer);成年人(Adult);老年人(Aged);CD4阳性T淋巴细胞(CD4-Positive T-Lymphocytes);CD8阳性T淋巴细胞(CD8-Positive T-Lymphocytes);女(雌)性(Female);流式细胞术(Flow Cytometry);人类(Humans);免疫因子类(Immunologic Factors);免疫疗法, 过继(Immunotherapy, Adoptive);干扰素α(Interferon-alpha);男(雄)性(Male);黑色素瘤(Melanoma);中年人(Middle Aged);皮肤肿瘤(Skin Neoplasms);存活率(Survival Rate);T淋巴细胞, 细胞毒性(T-Lymphocytes, Cytotoxic);治疗结果(Treatment Outcome)
DOI
10.1007/s00262-011-1004-8
PMID
21431917
发布时间
2021-10-20
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