换一批Rap1a activation by CalDAG-GEFI and p38 MAPK is involved in E-selectin-dependent slow leukocyte rolling.
第一作者：
Anika,Stadtmann
第一单位：
Department of Anesthesiology and Intensive Care Medicine, University of Münster, Münster, Germany; Max-Planck Institute Münster, Münster, Germany.
作者：
医学主题词
动物(Animals);Ib类磷脂酰肌醇3-激酶(Class Ib Phosphatidylinositol 3-Kinase);E选择素(E-Selectin);GTP结合蛋白α亚基, Gi2(GTP-Binding Protein alpha Subunit, Gi2);鸟嘌呤核苷酸交换因子类(Guanine Nucleotide Exchange Factors);整合素类(Integrins);白细胞滚动(Leukocyte Rolling);淋巴细胞功能相关抗原1(Lymphocyte Function-Associated Antigen-1);小鼠(Mice);小鼠, 近交C57BL(Mice, Inbred C57BL);小鼠, 基因敲除(Mice, Knockout);中性白细胞浸润(Neutrophil Infiltration);中性白细胞(Neutrophils);腹膜炎(Peritonitis);百白咳毒素(Pertussis Toxin);磷脂酶Cγ(Phospholipase C gamma);信号传导(Signal Transduction);跨内皮和跨上皮迁移(Transendothelial and Transepithelial Migration);p38丝裂原活化蛋白激酶类(p38 Mitogen-Activated Protein Kinases);rap1 GTP结合蛋白质类(rap1 GTP-Binding Proteins);tat基因产物, 人免疫缺陷病毒(tat Gene Products, Human Immunodeficiency Virus)
DOI
10.1002/eji.201041196
PMID
21480213
发布时间
2025-05-29
基金项目
R01 HL094594/HL/NHLBI NIH HHS/United States
R01 HL058108-11/HL/NHLBI NIH HHS/United States
P0I HL056949/HL/NHLBI NIH HHS/United States
P01 HL056949/HL/NHLBI NIH HHS/United States
R01 HL058108/HL/NHLBI NIH HHS/United States
- 浏览87
European journal of immunology
2074-85页
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