Fetal neural tube stem cells from Pax3 mutant mice proliferate, differentiate, and form synaptic connections when stimulated with folic acid.
作者:
主题词
动物(Animals);细胞分化(Cell Differentiation);细胞增殖(Cell Proliferation);疾病模型, 动物(Disease Models, Animal);胚胎, 哺乳动物(Embryo, Mammalian);胎儿干细胞(Fetal Stem Cells);胎儿(Fetus);叶酸(Folic Acid);基因表达调控, 发育期(Gene Expression Regulation, Developmental);基因敲除技术(Gene Knockout Techniques);纯合子(Homozygote);小鼠(Mice);小鼠, 基因敲除(Mice, Knockout);神经干细胞(Neural Stem Cells);神经管(Neural Tube);神经元(Neurons);成对盒转录因子类(Paired Box Transcription Factors);受体, 成纤维细胞生长因子, 4型(Receptor, Fibroblast Growth Factor, Type 4);信号传导(Signal Transduction);椎管闭合不全(Spinal Dysraphism);突触(Synapses)
DOI
10.1089/scd.2011.0100
PMID
21521032
发布时间
2016-11-25
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Stem cells and development
321-30页
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