The activation of p38 MAPK primarily contributes to UV-induced RhoB expression by recruiting the c-Jun and p300 to the distal CCAAT box of the RhoB promoter.
第一作者:
Jiwon,Ahn
第一单位:
Genome Research Center, KRIBB, Daejeon 305-806, Republic of Korea.
作者:
医学主题词
转录激活因子2(Activating Transcription Factor 2);细胞凋亡(Apoptosis);CCAAT结合因子(CCAAT-Binding Factor);E1A相关p300蛋白质(E1A-Associated p300 Protein);酶激活(Enzyme Activation);基因表达调控(Gene Expression Regulation);人类(Humans);Jurkat细胞(Jurkat Cells);启动区, 遗传(Promoter Regions, Genetic);原癌基因蛋白质c-jun(Proto-Oncogene Proteins c-jun);转录, 遗传(Transcription, Genetic);紫外线(Ultraviolet Rays);p38丝裂原活化蛋白激酶类(p38 Mitogen-Activated Protein Kinases);ρB GTP结合蛋白质(rhoB GTP-Binding Protein)
DOI
10.1016/j.bbrc.2011.04.121
PMID
21565167
发布时间
2011-06-06
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