换一批
换一批Mechanistic rationale for inhibition of poly(ADP-ribose) polymerase in ETS gene fusion-positive prostate cancer.
作者：
主题词
动物(Animals);抗肿瘤药(Antineoplastic Agents);催化域(Catalytic Domain);细胞系, 肿瘤(Cell Line, Tumor);细胞运动(Cell Movement);鸡胚(Chick Embryo);染色质免疫沉淀法(Chromatin Immunoprecipitation);DNA损伤(DNA Damage);DNA活化蛋白激酶(DNA-Activated Protein Kinase);酶抑制剂(Enzyme Inhibitors);基因表达调控, 肿瘤(Gene Expression Regulation, Neoplastic);基因融合(Gene Fusion);基因, 报告(Genes, Reporter);HEK293细胞(HEK293 Cells);人类(Humans);男(雄)性(Male);质谱分析法(Mass Spectrometry);小鼠(Mice);小鼠, 近交BALB C(Mice, Inbred BALB C);小鼠, 裸(Mice, Nude);小鼠, SCID(Mice, SCID);模型, 分子(Models, Molecular);肿瘤侵润(Neoplasm Invasiveness);癌基因蛋白质类, 融合(Oncogene Proteins, Fusion);酞嗪类(Phthalazines);哌嗪类(Piperazines);聚ADP核糖聚合酶类(Poly(ADP-ribose) Polymerases);前列腺肿瘤(Prostatic Neoplasms);蛋白质构象(Protein Conformation);RNA干扰(RNA Interference);重组融合蛋白质类(Recombinant Fusion Proteins);时间因素(Time Factors);转录激活(Transcriptional Activation);转染(Transfection);肿瘤负荷(Tumor Burden);异种移植模型抗肿瘤试验(Xenograft Model Antitumor Assays)
DOI
10.1016/j.ccr.2011.04.010
PMID
21575865
发布时间
2021-10-20
- 浏览87
Cancer cell
664-78页
相似文献
- 中文期刊
- 外文期刊
- 学位论文
- 会议论文
