The clinically available NMDA receptor antagonist, memantine, exhibits relative safety in the developing rat brain.
第一作者:
Simon M,Manning
第一单位:
Department of Neurology, Children's Hospital Boston and Harvard Medical School, Boston, MA 02115, USA.
作者:
主题词
动物(Animals);动物, 新生(Animals, Newborn);细胞凋亡(Apoptosis);脑(Brain);地卓西平马来酸盐(Dizocilpine Maleate);兴奋性氨基酸拮抗剂(Excitatory Amino Acid Antagonists);人类(Humans);原位缺口末端标记(In Situ Nick-End Labeling);婴儿, 新生(Infant, Newborn);细胞内信号肽和蛋白质类(Intracellular Signaling Peptides and Proteins);白质软化病, 脑室周围(Leukomalacia, Periventricular);男(雄)性(Male);美金刚(Memantine);膜蛋白质类(Membrane Proteins);神经保护药(Neuroprotective Agents);蛋白质亚单位(Protein Subunits);大鼠(Rats);大鼠, Long-Evans(Rats, Long-Evans);受体, AMPA(Receptors, AMPA);受体, N-甲基-D-天冬氨酸(Receptors, N-Methyl-D-Aspartate);突触蛋白类(Synapsins)
DOI
10.1016/j.ijdevneu.2011.05.005
PMID
21624454
发布时间
2024-06-10
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