Cyclosporin A inhibits nucleotide excision repair via downregulation of the xeroderma pigmentosum group A and G proteins, which is mediated by calcineurin inhibition.
第一作者:
Christiane,Kuschal
第一单位:
Department of Dermatology, Venerology, and Allergology, Georg-August-University, Goettingen, Goettingen, Germany.
作者:
主题词
钙神经素(Calcineurin);细胞系(Cell Line);环孢菌素(Cyclosporine);DNA修复(DNA Repair);DNA结合蛋白质类(DNA-Binding Proteins);减量调节(Down-Regulation);内切核酸酶类(Endonucleases);成纤维细胞(Fibroblasts);人类(Humans);免疫抑制剂(Immunosuppressive Agents);核蛋白质类(Nuclear Proteins);RNA干扰(RNA Interference);RNA, 信使(RNA, Messenger);皮肤肿瘤(Skin Neoplasms);转录因子(Transcription Factors);移植物(Transplants);着色性干皮病(Xeroderma Pigmentosum);着色性干皮病蛋白A组(Xeroderma Pigmentosum Group A Protein)
DOI
10.1111/j.1600-0625.2011.01320.x
PMID
21707758
发布时间
2014-11-20
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