Genetic variability within the cholesterol lowering pathway and the effectiveness of statins in reducing the risk of MI.
第一作者:
Bas J M,Peters
第一单位:
Department of Pharmacoepidemiology and Pharmacotherapy, Utrecht Institute for Pharmaceutical Sciences, Utrecht University, Utrecht, The Netherlands.
作者:
主题词
ATP结合匣式转运子(ATP-Binding Cassette Transporters);老年人(Aged);病例对照研究(Case-Control Studies);卡方分布(Chi-Square Distribution);胆固醇(Cholesterol);女(雌)性(Female);基因型(Genotype);人类(Humans);羟甲基戊二酰基CoA还原酶抑制剂(Hydroxymethylglutaryl-CoA Reductase Inhibitors);高胆固醇血症(Hypercholesterolemia);脂肪酶(Lipase);脂蛋白类(Lipoproteins);Logistic模型(Logistic Models);男(雄)性(Male);中年人(Middle Aged);心肌梗死(Myocardial Infarction);荷兰(Netherlands);比值比(Odds Ratio);PPARγ(PPAR gamma);遗传药理学(Pharmacogenetics);表型(Phenotype);多态性, 单核苷酸(Polymorphism, Single Nucleotide);前蛋白转化酶类(Proprotein Convertases);登记(Registries);危险性评估(Risk Assessment);危险因素(Risk Factors);清道夫受体, B类(Scavenger Receptors, Class B);丝氨酸内肽酶类(Serine Endopeptidases);甾醇O-酰基转移酶(Sterol O-Acyltransferase);治疗结果(Treatment Outcome)
DOI
10.1016/j.atherosclerosis.2011.06.023
PMID
21741043
发布时间
2021-10-20
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Atherosclerosis
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