Genotyping NAT2 with only two SNPs (rs1041983 and rs1801280) outperforms the tagging SNP rs1495741 and is equivalent to the conventional 7-SNP NAT2 genotype.
第一作者:
Silvia,Selinski
第一单位:
Leibniz Research Centre for Working Environment and Human Factors (IfADo), Dortmund, Germany. selinski@ifado.de
作者:
医学主题词
乙酰化作用(Acetylation);芳基胺N-乙酰转移酶(Arylamine N-Acetyltransferase);咖啡因(Caffeine);病例对照研究(Case-Control Studies);女(雌)性(Female);基因型(Genotype);单倍型(Haplotypes);人类(Humans);连锁不平衡(Linkage Disequilibrium);男(雄)性(Male);表型(Phenotype);多态性, 单核苷酸(Polymorphism, Single Nucleotide);敏感性与特异性(Sensitivity and Specificity)
DOI
10.1097/FPC.0b013e3283493a23
PMID
21750470
发布时间
2021-12-03
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