Vascular endothelial growth factor is upregulated by L-dopa in the parkinsonian brain: implications for the development of dyskinesia.
第一作者:
K Elisabet,Ohlin
第一单位:
Department of Experimental Medical Science, Lund University, Lund, Sweden. elisabet.ohlin@med.lu.se
作者:
医学主题词
老年人(Aged);老年人, 80以上(Aged, 80 and over);方差分析(Analysis of Variance);动物(Animals);抗原, CD(Antigens, CD);抗原, 表面(Antigens, Surface);抗震颤麻痹药(Antiparkinson Agents);星形细胞(Astrocytes);行为, 动物(Behavior, Animal);苄丝肼(Benserazide);血管(Blood Vessels);血脑屏障(Blood-Brain Barrier);脑(Brain);溴脱氧尿苷(Bromodeoxyuridine);细胞计数(Cell Count);细胞, 培养的(Cells, Cultured);疾病模型, 动物(Disease Models, Animal);多巴胺(Dopamine);剂量效应关系, 药物(Dose-Response Relationship, Drug);运动障碍, 药物性(Dyskinesia, Drug-Induced);胚胎, 哺乳动物(Embryo, Mammalian);酶抑制剂(Enzyme Inhibitors);酶联免疫吸附测定(Enzyme-Linked Immunosorbent Assay);女(雌)性(Female);人类(Humans);层黏连蛋白(Laminin);左旋多巴(Levodopa);男(雄)性(Male);新生血管化, 病理性(Neovascularization, Pathologic);神经组织蛋白质类(Nerve Tissue Proteins);帕金森障碍(Parkinsonian Disorders);RNA, 信使(RNA, Messenger);大鼠(Rats);大鼠, Sprague-Dawley(Rats, Sprague-Dawley);时间因素(Time Factors);增量调节(Up-Regulation);血管内皮生长因子A(Vascular Endothelial Growth Factor A)
DOI
10.1093/brain/awr165
PMID
21771855
发布时间
2025-05-29
- 浏览12
Brain
2339-57页
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