换一批
换一批Immunity against a therapeutic xenoprotein/Fc construct delivered by gene transfer is reduced through binding to the inhibitory receptor FcγRIIb.
作者：
主题词
动物(Animals);抗体, 中和(Antibodies, Neutralizing);B-淋巴细胞(B-Lymphocytes);糖尿病, 2型(Diabetes Mellitus, Type 2);基因表达调控(Gene Expression Regulation);基因转移技术(Gene Transfer Techniques);降血糖药(Hypoglycemic Agents);免疫球蛋白Fc片段(Immunoglobulin Fc Fragments);注射, 肌肉内(Injections, Intramuscular);男(雄)性(Male);小鼠(Mice);小鼠, 近交C57BL(Mice, Inbred C57BL);小鼠, 基因敲除(Mice, Knockout);肽类(Peptides);质粒(Plasmids);蛋白质结合(Protein Binding);受体, IgG(Receptors, IgG);重组融合蛋白质类(Recombinant Fusion Proteins);转导, 遗传(Transduction, Genetic);毒液类(Venoms)
DOI
10.1002/jgm.1598
PMID
21786368
发布时间
2018-12-01
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