换一批
换一批Possible involvement of prolonging spinal µ-opioid receptor desensitization in the development of antihyperalgesic tolerance to µ-opioids under a neuropathic pain-like state.
作者：
主题词
镇痛药, 阿片类(Analgesics, Opioid);动物(Animals);剂量效应关系, 药物(Dose-Response Relationship, Drug);药物耐受性(Drug Tolerance);女(雌)性(Female);芬太尼(Fentanyl);GTP结合蛋白质类(GTP-Binding Proteins);鸟苷5'-O-(3-硫代三磷酸)(Guanosine 5'-O-(3-Thiotriphosphate));热温度(Hot Temperature);痛觉过敏(Hyperalgesia);注射, 皮下(Injections, Subcutaneous);结扎术(Ligation);男(雄)性(Male);小鼠(Mice);小鼠, 基因敲除(Mice, Knockout);吗啡(Morphine);神经痛(Neuralgia);羟可酮(Oxycodone);疼痛测定(Pain Measurement);痛阈(Pain Threshold);放射配体测定(Radioligand Assay);受体, 阿片样, μ(Receptors, Opioid, mu);坐骨神经(Sciatic Nerve);氯化钠(Sodium Chloride);脊髓(Spinal Cord);β内啡肽(beta-Endorphin)
DOI
10.1111/j.1369-1600.2011.00354.x
PMID
21812868
发布时间
2021-10-20
- 浏览13
Addiction biology
614-22页
相似文献
- 中文期刊
- 外文期刊
- 学位论文
- 会议论文
