Discovery and assembly-line biosynthesis of the lymphostin pyrroloquinoline alkaloid family of mTOR inhibitors in Salinispora bacteria.

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第一作者： Akimasa,Miyanaga

第一单位： Center for Marine Biotechnology and Biomedicine, Scripps Institution of Oceanography, University of California at San Diego, La Jolla, California 92093-0204, United States.

作者： Akimasa,Miyanaga ^[1] ; Jeffrey E,Janso ; Leonard,McDonald ; Min,He ; Hongbo,Liu ; Laurel,Barbieri ; Alessandra S,Eustáquio ; Elisha N,Fielding ; Guy T,Carter ; Paul R,Jensen ; Xidong,Feng ; Margaret,Leighton ; Frank E,Koehn ; Bradley S,Moore

作者单位： Center for Marine Biotechnology and Biomedicine, Scripps Institution of Oceanography, University of California at San Diego, La Jolla, California 92093-0204, United States. ^[1]

主题词放线菌目(Actinomycetales);生物碱类(Alkaloids);酶抑制剂(Enzyme Inhibitors);吡咯类(Pyrroles);喹啉类(Quinolines);TOR丝氨酸-苏氨酸激酶(TOR Serine-Threonine Kinases)

DOI 10.1021/ja205655w

PMID 21815669

发布时间 2024-03-22

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